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Laboratory of Pharmaceutics,
Faculty of Pharmaceutical Science,
Toho University

Miyama2-2-1, Funabashi,
Chiba, 274-8510 Japan

Laboratory of Pharmaceutics

About us

    The functional characteristics of pharmaceutics are strongly dependent on their physicochemical and structural properties. A detailed understanding of the physicochemical and structural properties of active pharmaceutical ingredients (APIs), as well as the excipients used during the formulation of pharmaceutics, is therefore essential for developing new pharmaceutics. Research in our group is primarily focused on investigating the physicochemical and structural properties of APIs, as well as elucidating the structure–function relationships of pharmaceutics using various analytical methods. The results of our research have been applied to the design of novel pharmaceutics with improved functional characteristics.

   Our current research interests fall into the following categories:
  1. Investigating the physicochemical and structural properties of the different polymorphic crystalline forms, salt crystals and co-crystals of various APIs.
  2. Evaluating the polymorphic transitions of crystalline APIs.
  3. Developing new formulation systems to improve the solubility of highly-insoluble APIs.
  4. Developing new simulation methods for predicting the oral absorption characteristics of APIs based on the physicochemical theories.
  5. Elucidating the functional characteristics of pharmaceutics based on their three-dimensional structures.
  6. Developing new methods for evaluating the physicochemical properties of APIs and analyzing the structural characteristics of pharmaceutics (e.g., the use of synchrotron X-ray radiation).