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東邦大学
理学部生物分子科学科
曽根研究室

〒274-8510
千葉県船橋市三山2-2-1
習志野学事部入試広報課
TEL 047-472-0666
E-mail:
masaki.sone (アットマーク)
sci.toho-u.ac.jp

研究業績

 

主要原著論文

Systematic analysis of fly models with multiple drivers reveals different effects for Ataxin-1 and Huntingtin in neuron subtype-specific expression.
Risa Shiraishi, Takuya Tamura, Masaki Sone, Hitoshi Okazawa
PLoS One, 9, e116567 (2014).
Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.
Sam S Barclay, Takuya Tamura, Hikaru Ito, Kyota Fujita, Kazuhiko Tagawa, Teppei Shimamura, Asuka Katsuta, Hiroki Shiwaku, Masaki Sone, Seiya Imoto, Satoru Miyano, Hitoshi Okazawa
Hum. Mol. Genet., 23, 1345-1364 (2014).

PubMed

A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.
Kyota Fujita, Yoko Nakamura, Tsutomu Oka, Hikaru Ito, Takuya Tamura, Kazuhiko Tagawa, Toshikazu Sasabe, Asuka Katsuta, Kazumi Motoki, Hiroki Shiwaku, Masaki Sone, Chisato Yoshida, Masahisa Katsuno, Yoshinobu Eishi, Miho Murata, J. Paul Taylor, Erich E. Wanker, Kazuteru Kono, Satoshi Tashiro, Gen Sobue, Albert R. La Spada, Hitoshi Okazawa
Nature Commun., 4, 1816 (2013).

PubMed

A restricted level of PQBP1 is needed for the best longevity of Drosophila.
Takuya Tamura, Masaki Sone, Yoko Nakamura, Teppei Shimamura, Seiya Imoto, Satoru Miyano, Hitoshi Okazawa
Neurobiol. Aging, 34, 356.e11-356.e20 (2013).

PubMed

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
Takuya Tamura, Masaki Sone, Takeshi Iwatsubo, Kazuhiko Tagawa, Erich E. Wanker, Hitoshi Okazawa
PLoS One, 6, e27408 (2011). 

PubMed

Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning.
Takuya Tamura, Daisuke Horiuchi, Yi-Chung Chen, Masaki Sone, Tomoyuki Miyashita, Minoru Saitoe, Natsue Yoshimura, Ann-Shyn Chiang, Hitoshi Okazawa
J. Neurosci., 30, 14091-14101 (2010). 

PubMed

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.
Hiroki Shiwaku, Natsue Yoshimura, Takuya Tamura, Masaki Sone, Soichi Ogishima, Kei Watase, Kazuhiko Tagawa, Hitoshi Okazawa
EMBO J., 29, 2446-2460 (2010). 

PubMed

Mutant huntingtin impairs Ku70-mediated DNA repair.
Yasushi Enokido, Takuya Tamura, Hikaru Ito, Anup Arumughan, Akihiko Komuro, Hiroki Shiwaku, Masaki Sone, Raphaele Foulle, Hirohide Sawada, Hiroshi Ishiguro, Tetsuya Ono, Miho Murata, Ichiro Kanazawa, Nikolai Tomilin, Kazuhiko Tagawa, Erich E Wanker, Hitoshi Okazawa
J. Cell Biol., 189, 425-443 (2010). 

PubMed