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東邦大学
理学部生物分子科学科
曽根研究室

〒274-8510
千葉県船橋市三山2-2-1
習志野学事部入試広報課
TEL 047-472-0666
E-mail:
masaki.sone (アットマーク)
sci.toho-u.ac.jp

研究業績

 

主要原著論文

Design and synthesis of gene-directed caged cyclin nucleotides exhibiting cell type selectivity.
Akinobu Z Suzuki, Taichi Sakano, Hirona Sasaki, Rei Watahiki, Masaki Sone, Kazuki Horikawa, Toshiaki Furuta
Chem. Commun., 57, 5630-5633 (2021).

Pubmed

DNA damage in embryonic neural stem cell determines FTLD's fate via early-stage neuronal necrosis.
Hidenori Homma, Hikari Tanaka, Meihua Jin, Xiaocen Jin, Yong Huang, Yuki Yoshioka, Christian JF Bertens, Kohei Tsumaki, Kanoh Kondo, Hiroki Shiwaku, Kazuhiko Tagawa, Hiroyasu Akatsu, Naoki Atsuta, Masahisa Katsuno, Katsutoshi Furukawa, Aiko Ishiki, Masaaki Waragai, Gaku Ohtomo, Atsushi Iwata, Takanori Yokota, Haruhisa Inoue, Hiroyuki Arai, Gen Sobue, Masaki Sone, Kyota Fujita, Hitoshi Okazawa
Life Sci. Alliance, 4, e202101022 (2021).

Pubmed

Journal Link

Cyclin D1 controls development of cerebellar granule cell progenitors through phosphorylation and stabilization of ATOH1.
Satoshi Miyashita, Tomoo Owa, Yusuke Seto, Mariko Yamashita, Shogo Aida, Masaki Sone, Kentaro Ichijo, Tomoki Nishioka, Kozo Kaibuchi, Yoshiya Kawaguchi, Shinichiro Taya, Mikio Hoshino
EMBO J. 40, e105712 (2021).

Pubmed

Role of the Drosophila YATA protein in the proper subcellular localizatioin of COPI revealed by in vivo analysis.
Maiko Saito, Minoru Nakayama, Kyota Fujita, Atsuko Uchida, Hiroyuki Yano, Satoshi Goto, Hitoshi Okazawa, Masaki Sone
Genes Genet. Syst. 95, 303-314 (2021).

Pubmed

Journal Link

AUTS2 regulation of synapses for proper synaptic inputs and social communication.
Kei Hori, Kunihiko Yamashiro, Taku Nagai, Wei Shan, Saki F. Egusa, Kazumi Shimaoka, Hiroshi Kuniishi, Masayuki Sekiguchi, Yasuhiro Go, Shoji Tatsumoto, Mitsuyo Yamada, Reika Shiraishi, Kouta Kanno, Satoshi Miyashita, Asami Sakamoto, Manabu Abe, Kenji Sakimura, Masaki Sone, Kazuhiro Sohya, Hiroshi Kunugi, Keiji Wada, Mitsuhiko Yamada, Kiyofumi Yamada, Mikio Hoshino
iScience 23, 101183 (2020).

Pubmed

Analysis of a cellular structure observed in the compound eyes of Drosophila white; yata mutants and white mutants.
Eri Arimoto*, Yutaro Kawashima*, Taein Choi, Mami Unagami, Shintaro Akiyama, Mizuki Tomizawa, Hiroyuki Yano, Emiko Suzuki, Masaki Sone
Biology Open 9, bio047043 (2020).
(*: equal contribution)

Pubmed

Suppression of the synaptic localization of a subset of proteins including APP partially ameliorates phenotypes of the Drosophila Alzheimer's disease model.
Koto Furotani, Keisuke Kamimura, Takaaki Yajima, Minoru Nakayama, Rena Enomoto, Takuya Tamura, Hitoshi Okazawa, Masaki Sone
PLoS One, 13, e0204048 (2018).

内容の紹介はこちら

Pubmed

Characterization of the activity of beta-galactosidase from Escherichia coli and Drosophila melanogaster in fixed and non-fixed Drosophila tissues.
Mizuki Tomizawa*, Kohei Tsumaki*, Masaki Sone
Biochimie Open, 3, 1-7 (2016).
(*: equal contribution)

Pubmed

Systematic analysis of fly models with multiple drivers reveals different effects for Ataxin-1 and Huntingtin in neuron subtype-specific expression.
Risa Shiraishi, Takuya Tamura, Masaki Sone, Hitoshi Okazawa
PLoS One, 9, e116567 (2014).

Pubmed

Systems biology analysis of Drosophila in vivo screen data elucidates core networks for DNA damage repair in SCA1.
Sam S Barclay, Takuya Tamura, Hikaru Ito, Kyota Fujita, Kazuhiko Tagawa, Teppei Shimamura, Asuka Katsuta, Hiroki Shiwaku, Masaki Sone, Seiya Imoto, Satoru Miyano, Hitoshi Okazawa
Hum. Mol. Genet., 23, 1345-1364 (2014).

PubMed

A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases.
Kyota Fujita, Yoko Nakamura, Tsutomu Oka, Hikaru Ito, Takuya Tamura, Kazuhiko Tagawa, Toshikazu Sasabe, Asuka Katsuta, Kazumi Motoki, Hiroki Shiwaku, Masaki Sone, Chisato Yoshida, Masahisa Katsuno, Yoshinobu Eishi, Miho Murata, J. Paul Taylor, Erich E. Wanker, Kazuteru Kono, Satoshi Tashiro, Gen Sobue, Albert R. La Spada, Hitoshi Okazawa
Nature Commun., 4, 1816 (2013).

PubMed

A restricted level of PQBP1 is needed for the best longevity of Drosophila.
Takuya Tamura, Masaki Sone, Yoko Nakamura, Teppei Shimamura, Seiya Imoto, Satoru Miyano, Hitoshi Okazawa
Neurobiol. Aging, 34, 356.e11-356.e20 (2013).

PubMed

Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
Takuya Tamura, Masaki Sone, Takeshi Iwatsubo, Kazuhiko Tagawa, Erich E. Wanker, Hitoshi Okazawa
PLoS One, 6, e27408 (2011). 

PubMed

Drosophila PQBP1 regulates learning acquisition at projection neurons in aversive olfactory conditioning.
Takuya Tamura, Daisuke Horiuchi, Yi-Chung Chen, Masaki Sone, Tomoyuki Miyashita, Minoru Saitoe, Natsue Yoshimura, Ann-Shyn Chiang, Hitoshi Okazawa
J. Neurosci., 30, 14091-14101 (2010). 

PubMed

Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.
Hiroki Shiwaku, Natsue Yoshimura, Takuya Tamura, Masaki Sone, Soichi Ogishima, Kei Watase, Kazuhiko Tagawa, Hitoshi Okazawa
EMBO J., 29, 2446-2460 (2010). 

PubMed

Mutant huntingtin impairs Ku70-mediated DNA repair.
Yasushi Enokido, Takuya Tamura, Hikaru Ito, Anup Arumughan, Akihiko Komuro, Hiroki Shiwaku, Masaki Sone, Raphaele Foulle, Hirohide Sawada, Hiroshi Ishiguro, Tetsuya Ono, Miho Murata, Ichiro Kanazawa, Nikolai Tomilin, Kazuhiko Tagawa, Erich E Wanker, Hitoshi Okazawa
J. Cell Biol., 189, 425-443 (2010). 

PubMed