研究業績

• Izumi T, Saito A, Ida T, Mukuda T, Katayama Y, Wong MKS, Tsukada T. Paracrine and endocrine pathways of natriuretic peptides assessed by ligand-receptor mapping in Japanese eel brain. Cell Tiss Res (2024)

• Wong MKS, Tsuneoka Y, Tsukada T. Subcellular localization of Na⁺/K⁺-ATPase isoforms resolved by in situ hybridization chain reaction in the gill of chum salmon at freshwater and seawater. Fish Physiol Biochem (2023) 
• Katayama Y, Tsukada T, Hyodo S, Sakamoto H, Sakamoto T. Behavioural osmoregulation during land invasion in fish: prandial drinking and wetting of the dry skin. PLOS One (2022)
• Katayama Y, Saito A, Ogoshi M, Tsuneoka Y, Mukuda T, Azuma M, Kusakabe M, Takei Y, Tsukada T. Gene duplication of C-type natriuretic peptide-4 (CNP4) in teleost lineage elicits subfunctionalization of ancestral CNP. Cell Tiss Res (2022)
• Takei Y, Ando M, Wong MKS, Tsukada T. Molecular mechanisms underlying guanylin-induced transcellular Cl- secretion into the intestinal lumen of seawater-acclimated eels. Gene Comp Endocrinol (2022)
• Katayama Y, Wong MKS, Kusakabe M, Fujio M, Takahashi N, Yaguchi M, Tsukada T. Seawater transfer down-regulates C-type natriuretic peptide-3 expression in prolactin-producing cells of Japanese eel: negative correlation with plasma chloride concentration. Mol Cell Endocrinol (2020)
• Wong MKS, Uchida M, Tsukada T. Histological differentiation of mucus cell subtypes suggests functional compartmentation in the eel esophagus. Cell Tissue Res (2020)
• Tsukada T, Isowa Y, Kito K, Yoshida S, Toneri S, Horiguchi K, Fujiwara K, Yashiro T, Kato T, Kato Y. Identification of TGFβ-induced proteins in non-endocrine mouse pituitary cell line TtT/GF by SILAC-assisted quantitative mass spectrometry. Cell Tissue Res, 376: 281-293 (2019)
• Tsukada T, Yoshida S, Kito K, Fujiwara K, Yako H, Horiguchi K, Isowa Y, Yashiro T, Kato T, Kato Y. TGFβ signal reinforces pericyte properties of the non-endocrine mouse pituitary cell line TtT/GF. Cell Tissue Res, 371: 339-350 (2018) 
• Wong MKS, Tsukada T, Ogawa N, Pipil S, Ozaki H, Suzuki Y, Iwasaki W, Takei Y. A sodium binding system alleviates acute salt stress during seawater acclimation in eels. Zool Lett, 3:22 (2017)
• Tsukada T, Azuma M, Horiguchi K, Fujiwara K, Kouki T, Kikuchi M, and Yashiro T. Folliculostellate cell interacts with pericyte via TGFbeta2 in rat anterior pituitary. J Endocrinol, Vol 229: 159-170 (2016) 
• Tsukada T, Fujiwara K, Horiguchi K, AzumaM, RamadhaniD, Tofrizal A, Batchuluun K, Maliza R, Syaidah R, Kikuchi M, and Yashiro T. Folliculostellate cells are required for laminin release from gonadotrophs in rat anterior pituitary. Acta Histochem Cytochem, Vol. 47: 239–245 (2014)
• Tsukada T, Kouki T, Fujiwara K, Ramadhani D, Horiguchi K, Kikuchi M, and Yashiro T. Reassembly of anterior pituitary organization by hanging drop three-dimensional cell culture. Acta Histochem Cytochem, Vol. 46: 121-127 (2013). 
• Tsukada T, Kotlyanskaya L, Huynh R, Desai B, Novak SM, Kajava AV, Gregorio CC, and Kostyukova AS. Identification of residues within tropomodulin1 responsible for its localization at the pointed ends of the actin filaments in cardiac myocytes. J Biol Chem, Vol. 286: 2194-2204 (2011).
• Tsukada T, Pappas CT, Moroz N, Antin PB, Kostyukova AS, and Gregorio CC. Leiomodin2 is an Antagonist of Tropomodulin1 at the Pointed End of the Thin Filaments in Cardiac Muscle. J Cell Sci, Vol. 123: 3136-3145 (2010).
• Tsukada T, Nobata S, Hyodo S, and Takei Y. Area postrema, a brain circumventricular organ, is the site of antidipsogenic action of circulating atrial natriuretic peptide in eels. J Exp Biol, Vol. 210: 3970-3978 (2007).
• Tsukada T and Takei Y. Integrative approach to osmoregulatory action of atrial natriuretic peptide in seawater eels. Gene Comp Endocrinol, Vol. 147: 31-38 (2006).
• Tsukada T, Rankin JC, and Takei Y. Involvement of drinking and intestinal sodium absorption in hyponatremic effect of atrial natriuretic peptide in seawater eels. Zool Sci, Vol. 22: 77-85 (2005).
• Tsukada T and Takei Y. Relative potency of three homologous natriuretic peptide (ANP, CNP and VNP) in eel osmoregulation. Zool Sci, Vol. 18: 1253-1258 (2001). 

黄色のハイライトは塚田研の卒業生・OB/OG

• Tsukada T. Chapter 46 “Natriuretic peptide family” and Chapter 52 “Osteocrin” In H. Ando, K. Ukena, and S. Nagata (Eds.), Handbook of Hormones: Comparative and General Endocrinology. Second Edition, Elsevier, San Diego, CA. Pp 533-552, 601-604 (2021)
• Tsukada T. Chapter 32 “B-type natriuretic peptide”, “C-type natriuretic peptides” and “Ventricular natriuretic peptide”. In Y. Takei, H. Ando, and K. Tsutsui (Eds.), Handbook of Hormones: Comparative and General Endocrinology. Elsevier, San Diego, CA. Pp281-290 (2015)
• Takei Y and Tsukada T (2014). Evolution of Natriuretic Peptide System. In Reference Module in Biomedical Research. MJ Caplan (Eds), Elsevier, San Diego, CA.
• Tsukada T, Wong MK, Ogoshi M, and Yuge S (2013). Endocrine control of osmoregulation. In Eel Physiology. F Trischitta, Y Takei and P Sebert (Eds.), CRC Press, Boca Raton, FL.

• ハマー＆マクフィー　疾患の病態生理−臨床医学入門　原書7版（Pathophysiology of Disease: An Introduction to Clinical Medicine 7^thEd.）。丸善出版。第19章：視床下部・下垂体の障害。Pp 577-601, 2019. ISBN-10: 4621303880

• Endo A, Miyauchi A, Aoki M, Koyanagi T, Goto M, Wong MKS, and Tsukada T 

• Tsukada T
  Cell to cell and cell to extracellular matrix interactions in anterior pituitary gland. The 12th Nikko International Symposium 2015. Tochigi, Japan, 2015
• Tsukada T
  International Workshop on Recent Advance Researching Method of Morphology. Ulan Bator, Mongolia, 2015
• Tsukada T, Azuma M, Ramadhani D, Batchuluun K, and Yashiro T.
  Folliculostellate Cells Are Required for Laminin Release from Gonadotrophs in Rat Anterior Pituitary Gland. 16th International Congress of Endocrinology and The Endocrine Society’s 96th Annual Meeting & Expo. Chicago, IL, USA, 2014
• Tsukada T, Fujiwara K, Ramadhani D, Kouki T, Kikuchi M, and Yashiro T.
  Folliculostellate cells interact with microvessel mural cell ‘pericyte’ to maintain collagen arrangement in rat anterior pituitary. The Endocrine Society’s 95th Annual Meeting & Expo. San Francisco, CA, USA, 2013
• Tsukada T and Yashiro T
  Workshop On Immunohistochemical Method as An Important Basic Diagnostic Tool in Medical Science. Padang, Indonesia, 2011
• Tsukada T
  Introduction of the 3 dimensional cell culture system into pituitary research. International Symposium on A New Regulatory System of Anterior Pituitary Cell Function and Its Clinical Impact. Padang, Indonesia, 2011
• Tsukada T, Pappas CT, Moroz N, Antin PB, Kostyukova AS, and Gregorio CC
  Leiomodin2 is an Antagonist of Tropomodulin1 at the Pointed End of the Thin Filaments in Cardiac Muscle. 50th American Society for Cell Biology Annual Meeting. Philadelphia, PA, USA, 2010
• Tsukada T, Kotlyanskaya L, Gregorio CC, Kostyukova AS
  Leucine rich repeat (LRR) domain of tropomodulin is responsible for targeting it to the pointed end of the actin filament. 54th Biophysical Society Annual Meeting. San Francisco, CA, USA, 2010
• Tsukada T, Dorovkov M, Kotlyanskaya L, Shah S, Nworu C, Kostyukova AS, Gregorio CC
  Phosphorylation of Tmod1 Thr54 Prevents Efficient Assembly at Thin Filament Pointed Ends. 49th American Society for Cell Biology Annual Meeting. San Diego, CA, USA, 2009
• Tsukada T, Ono Y, Bliss K and Gregorio CC
  Disruption in the tropomodulin1 (Tmod1) gene compromises cardiomyocyte development in murine embryonic stem cells by arresting myofibril maturation. 17th International Congress of the Federation of Associations of Anatomists. Cape Town, South Africa, 2009
• Tsukada T, Hyodo S and Takei Y
  Brain target sites for the antidipsogenic effect of atrial natriuretic peptide (ANP) in eels. The 15th International Congress of Comparative Endocrinology. Boston, MA, USA, 2005
• Tsukada T and Takei Y
  Effects of endogenous ANP and VNP on eel osmoregulation as evaluated by immunoneutralization. 5th Congress of the Asia and Oceania Society for Comparative Endocrinology. Nara, Japan, 2004
• Tsukada T and Takei Y
  ANP-mediated hyponatremia is due to an inhibitory action of ANP on drinking and intestinal NaCl absorption in seawater-adapted eels. International Symposium on Function of Marine Organisms. Mechanisms of Adaptation to Diverse Environments. Tokyo, Japan, 2003
• Tsukada T and Takei Y
  Mechanisms underlying hyponatremic effect of atrial natriuretic peptide in seawater eels. 4th Intercongress Symposium of the Asia and Oceania Society for Comparative Endocrinology. Guangzhou, China, 2002

黄色のハイライトは塚田研の卒業生・OB/OG